Chronic pain affects a lot of the world's developed countries. Unfortunately, many data demonstrate that current medication does not provide adequate outcomes, with fewer than 70% of patients experiencing pain alleviation. Opioids are considered the backbone for chronic pain nowadays, including neuropathic and cancer pain. Opioids' intrinsic side effects are a major source of worry. All too frequently, these patients get addicted to opioids medicines, which can lead to tolerance and physical dependency and a variety of side effects, including sleepiness and constipation because of overdose. As a result, tremendous effort is put out to identify alternative techniques and give alternatives with improved safety profiles and equivalent efficacy. Compared to opioid-based medicines, cannabis can be an effective pain therapy that minimizes the risk of addiction and eliminates the risk of deadly overdose. Medical marijuana users believe that it is just as effective as, if not more effective than, opioid-based pain medications.


The difference between opioids and cannabis? 

What is CBD?

CBD is one of the cannabis plant's hundreds of active chemical components. Cannabinoids are the term given to these chemical molecules. They are classified as phyto-cannabinoid since they are derived from plants. Cannabis, the Cannabinoid-producing plant, has been utilized for millennia for many reasons, including pain treatment and stress alleviation. The discovery of CBD in humans has recently cleared the way for more widespread uses. Aside from their decreased danger of addiction or dependency and relative safety, their natural source and widespread usage have prompted more research into their therapeutic potential.


What are Opioids?

Opium is a plant that contains opioids, which attach to opioid receptors and relieve pain. Cannabis is a plant that contains cannabinoids, which act on Cannabinoid receptors to cause a variety of effects. Several opioids, including heroin, are classified as narcotics by the Drug Enforcement Administration. They also classify cannabis, hemp, and cannabinoids as illegal substances. It indicates the DEA considers cannabis and heroin to be similar dangers to society with no medicinal value.


How Does CBD Work?

CBD, unlike other cannabinoids, does not bind to the cannabinoid receptors. Instead, it operates by affecting other ECS components, resulting in various benefits, including pain alleviation. Scientists are currently attempting to determine how CBD products interact with the endocannabinoid system as a whole to produce its possible pain-relieving benefits. CBD may also aid with pain relief by blocking the transmission of pain signals to the brain's processing centers. Some of the Best CBD products also soothe pain and decrease pain feeling by causing the neurotransmitter adenosine to reuptake. CBD will assist in reducing pain feelings by increasing adenosine levels in the brain. Both opioids and CBD operate on numerous receptors in the body to provide pain-relieving effects. However, it appears that one has more negative side effects than the other.


How do opioids work?

Opioids including fentanyl, oxycodone, hydrocodone, and morphine are well-known. They are a group of medicines that work by interacting with opioid receptors on nerve cells in the brain and body to provide pain relief and euphoria. Prescriptions for these medications have been on the rise, as they have overdosed from their use. The regions of the brain and body with the highest concentrations of opioid receptors are where death occurs in an opioid overdose. The spinal cord, limbic system, and brainstem are three primary sites of these high-density regions. The medulla, a portion of the brain that controls the body's autonomous, non-voluntary processes, including breathing and heart rate, is part of the brainstem. Overdosing causes heart failure and respiratory failure because the brain regions with the largest concentrations of opioids receptors become depressed. Opioids addiction is a very common occurrence, and once addicted, it may be tough to break free. According to the CDC, anybody who uses prescription opioids has a chance of becoming addicted to them. Nearly one out of every four patients who get long-term opioids treatment in a primary care environment develops an addiction to the drug.


Why choose CBD for pain relief over opioids?

While both cannabis and opioids help treat pain, cannabis has never been connected to mortality due to a fatal dose. At the same time, the CDC says that opioids are involved in more than three out of every five drug overdose deaths. So, why are opioids used to alleviate pain? Opioids are easy to get and use due to their legal availability and broad societal acceptability. Because the DEA considers most opioids to be drugs, a variety of them can be marketed to you and prescribed by healthcare providers at their discretion. Cannabis and cannabinoids are classified as Schedule I narcotics, The Farm Bill passed in 2018 only makes CBD with 0.3 THC legal among other Cannabinoids, rendering other High THC cannabis or cannabis-derived treatments illegal in the United States. Of course, regardless of municipal or state legality, the federal government is beginning to view cannabis as having more therapeutic benefit.



Future studies should explore the impact of utilizing cannabis as medication-assisted treatment for opioids dependency and follow clinical results when cannabis is given as a realistic pain treatment alternative. CBD products can dramatically reduce consumption and enhance chronic pain and sleep quality in people which are already taking opioids for pain relief. CBD is more effective than opioids, according to the research.